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coley
2023-04-28T17:04:06+00:00
coley中文(简体)翻译：剑桥词典 Cambridge Dictionary
coley翻译：绿青鳕;绿青鳕鱼肉。。 示例中的观点不代表剑桥词典编辑、剑桥大学出版社和其许可证颁发者的观点。2021年11月18日 100多年前，美国纽约骨科医生William Coley意外发现术后化脓性链球菌感染使肉瘤患者肿瘤消退，揭开了肿瘤免疫疗法的序幕，William Coley因此被誉为肿瘤免 专访｜肿瘤免疫疗法如何发挥更优？国内青年科学家开发新策略Coley is a torpedoshaped fish with three triangular dorsal fins and a potbellied appearance It has a gray meat, lower value than other members Coley Description, Habitat, Image, Diet, and
COLEY中文(繁體)翻譯：劍橋詞典 Cambridge Dictionary
coley 在英語中文（繁體）詞典中的翻譯 coley noun [ C or U ] uk / ˈkəʊli / us / ˈkoʊli / plural coley Add to word list a fish that lives in the North Atlantic, or the flesh of this fish 2014年8月20日 美国纽约市的外科医生威廉科莱（William Coley）是个将这种方法运用在实际治疗中的人。 在19世纪90年代，他开始向癌症患者体内注射活的链球菌来治疗 癌症治疗，来针致病菌试试？ 果壳 科技有意思2023年12月4日 The father of immunotherapy, as William B Coley became known, was the model for the modern clinicianscientist He developed his theory that the immune William B Coley American Association for Cancer Research (AACR)
Revisiting Coley’s Toxins: Immunogenic Cardiolipins from
William B Coley (18621936), a bone sarcoma surgeon, was a pioneer in treating his patients with both live bacterialbased and mixture of heatkilled bacteria known as 2020年4月9日 The Story of Coley’s Toxins William Coley, often regarded as the “Father of Immunotherapy”, was a bone surgeon in New York from 1890–1936 who famously Talkin’ Toxins: From Coley’s to Modern Cancer Immunotherapy2018年10月2日 由于Coley Toxin本就不是主流 (只对肉瘤等一部分类型的肿瘤有效)，也很少有医生愿意花费精力研究它的有效性 (60年代至今有过一些小规模相关临床 肿瘤免疫疗法是如何诞生的？36氪
肿瘤免疫治疗不稀奇，120年前就有了！Coley
2020年6月1日 Coley毒素最后没有获得推广的主要原因就是别人不能重复出他的成功。根据书里介绍，没有重复出来临床数据的原因有很多，比如毒素的制备没有标准化（浓度，有效成分），治疗的步骤也没有标准化（剂 2021年2月24日 图3所示。个病人Coley治疗故意诱导丹毒(Coley, 1896a)。颈部大病变经治疗后消失;患者保持健康8年，然后死于复发(Coley, 1909)。 虽然科利并不是个尝试用细菌感染治疗癌症的人(这一称号 感染细菌治好了绝症科利Connor W Coley Achieving autonomous multistep synthesis of novel molecular structures in chemical discovery processes is a goal shared by many researchers In this Comment, we discuss key Connor W Coley's research
What Ever Happened to Coley’s Toxins? Cancer Research
2015年4月2日 In 1965, the American Cancer Society added Coley’s toxins to its “Unproven Methods of Cancer Therapy” This inclusion effectively marked Coley’s toxins as beyond the pale among mainstream cancer researchers The ACS would eventually remove Coley’s Toxins from the list (10 years later) but by then the damage had been done以下是老外对英文名Coley的看法，并把英文翻译成中文，让大家知道 Coley 英文名外国人眼中是什么样的真实看法和感受！ Mango 译 每当在给孩子起英文名字的时候我都会犯难，幸好听取了起名专家的建议，这个Coley，我很喜欢，读音也很明亮，洋气感十足。Coley英文名Coley英文名什么意思科利Coley名字寓意起名网2022年9月30日 邵 峰 院 士 9月27日，美国癌症研究所公布2022年 威廉科利奖 （ William B Coley Award ）获奖者名单，我所邵峰院士因其在 细胞焦亡领域的原创性发现与其他三位杰出科学家Judy Lieberman，H ao Wu和Vishva Dixit共获殊荣。 他们的工作 发现了细胞焦亡过程中在膜上打孔的gasdermin蛋白家族（GSDM)，并发现细胞焦亡 邵峰院士荣获2022年威廉科利奖 新闻动态 北京生命科学
Revisiting Coley’s Toxins: Immunogenic Cardiolipins from
Coley’s toxins, an early and enigmatic form of cancer (immuno)therapy, were based on preparations of Streptococcus pyogenes As part of a program to explore bacterial metabolites with immunomodulatory potential, S pyogenes metabolites were assayed in a cellbased immune assay, and a single membrane lipid, 18:1/18:0/18:1/18:0 cardiolipin, 2023年11月27日 COLEY definition: any of various edible fishes , esp the coalfish Meaning, pronunciation, translations and examplesCOLEY definition and meaning Collins English Dictionary2013年12月18日 Metrics William Coley found a way to prompt the immune system to fight cancer over a century ago After years of neglect, scientists are now seeking to replicate his success One day in October Bacteriology: A caring culture Nature
威廉科利百度百科
威廉科利，男，癌症 免疫治疗 之先驱。 [12] 曾任纽约癌症医院（New York Cancer Hospital，纪念斯隆－凯特琳癌症中心的前身）的外科医生。 威廉科利就曾试图用高温杀死的细菌刺激免疫系统，从而对抗 恶性肿瘤。科利发现，一些在癌症手术后发生感染的患者，存活的时间似乎更长，他由此猜想 coley翻译：绿青鳕;绿青鳕鱼肉。。 示例中的观点不代表剑桥词典编辑、剑桥大学出版社和其许可证颁发者的观点。coley中文(简体)翻译：剑桥词典 Cambridge DictionaryComputer assistance in synthesis design has existed for over 40 years, yet retrosynthesis planning software has struggled to achieve widespread adoption One critical challenge in developing highquality pathway suggestions is that proposed reaction steps often fail when attempted in the laboratory, despite initially seeming viable The true measure of success Prediction of Organic Reaction Outcomes Using Machine
Analyzing Learned Molecular Representations for Property
Advancements in neural machinery have led to a wide range of algorithmic solutions for molecular property prediction Two classes of models in particular have yielded promising results: neural networks applied to computed molecular fingerprints or expertcrafted descriptors and graph convolutional neural networks that construct a learned molecular 2023年12月4日 The father of immunotherapy, as William B Coley became known, was the model for the modern clinicianscientist He developed his theory that the immune system could be stimulated to fight and ultimately shrink a tumor by following the logical steps in the research process: First, he combed the literature for effective treatments; then developed William B Coley American Association for Cancer Research (AACR)Definition of coley noun in Oxford Advanced Learner's Dictionary Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and morecoley noun Definition, pictures, pronunciation and usage
The Toxins of William B Coley and the Treatment of Bone
The first systematic study of immunotherapy for the treatment of malignant tumors was begun in 1891 by William B Coley (18621936), a bone sarcoma surgeon ( Figure 1 ) Coley injected streptococcal organisms into a cancer patient in order to cause erysipelas and stimulate the immune system The patient's tumor disappeared, presumably because 2007年11月15日 Acquisition Will Expand Pfizer’s Investment in Vaccines, Broaden Scope of Research in a Number of Key Therapeutic Areas ( BUSINESS WIRE )Pfizer Inc (NYSE: PFE) announced today it has entered into an agreement to acquire Coley Pharmaceutical Group, Inc (NASDAQ: COLY), a publiclyheld biopharmaceutical company specializing Pfizer to Acquire Coley Pharmaceutical Group PfizerCW Coley, DA Thomas III, JAM Lummiss, JN Jaworski, CP Breen, Science 365 (6453), eaax1566, 2019 593 * 2019: A graphconvolutional neural network model for the prediction of chemical reactivity CW Coley, W Jin, L Rogers, TF Jamison, TS Jaakkola, WH Green, Connor W Coley Google Scholar
coley汉语(繁体)翻译：剑桥词典 Cambridge Dictionary
coley翻译：綠青鱈；綠青鱈魚肉。。 想要学更多吗？ Improve your vocabulary with English Vocabulary in Use from CambridgeLearn the words you need to communicate with confidencePeople Bio: Connor W Coley is the Class of 1957 Career Development Professor and an Assistant Professor at MIT in the Department of Chemical Engineering and the Department of Electrical Engineering and Computer Science He received his BS and PhD in Chemical Engineering from Caltech and MIT, respectively, and did his postdoctoral People – Coley Research GroupThe first microbial treatment of cancer were Coley's toxins These were followed by the introduction, in the 1970s, of Mycobacterium bovis BCG, as a treatment for bladder cancer In the past two decades, concomitant with the expansion of the field of cancer immunotherapy, there has been increased interest in using microbial agents to treat cancerColey's Toxins an overview ScienceDirect Topics
Using Computational Tools for Molecule Discovery ILP
Using Computational Tools for Molecule Discovery Connor Coley, an assistant professor of chemical engineering, is developing computational tools that would be able to predict molecular behavior and learn from the successes and mistakes By: Steve Calechman Discovering a drug, material or anything new requires finding and understanding moleculesPatterns 4 ( 2): ( 2023) [c13] Keir Adams, Connor W Coley: Equivariant ShapeConditioned Generation of 3D Molecules for LigandBased Drug Design ICLR 2023 [i36] Samuel Goldman, John Bradshaw, Jiayi Xin, Connor W Coley: Prefixtree Decoding for Predicting Mass Spectra from Molecules CoRR abs/230306470 ( 2023)dblp: Connor W ColeyCOLEY翻譯：綠青鱈;綠青鱈魚肉。。 示例中的觀點不代表劍橋詞典編輯、劍橋大學出版社和其許可證頒發者的觀點。COLEY中文(繁體)翻譯：劍橋詞典 Cambridge Dictionary
Coley Toxins — The First Century SpringerLink
The treatment of malignant tumors by bacterial toxins, as developed by the late William B Coley, MD, reviewed in the light of modern research Cancer Research 6: 205–216, 1946 Nauts, HD: Beneficial effects of immunotherapy (bacterial toxins) on sarcoma of the soft tissues, other than lymphosarcome2017年6月27日 科利去世后，他的女儿 Helen Coley Nauts (1907– 2001) 对科利的研究资料进行了进一步梳理，并发现科利毒素的治疗效果与癌症患者的治疗周期、引起的发热情况相关。 1953年，Coley Nauts 为纪念父亲，发起了一个非盈利性组织：癌症研究所（ ，CRI ）。科利毒素（Coley’s Toxins）:癌症免疫疗法投石问路分析化学2020年4月9日 Milestones in the History of Cancer Immunotherapy 21 The Story of Coley’s Toxins William Coley, often regarded as the “Father of Immunotherapy”, was a bone surgeon in New York from 1890–1936 who famously developed a cocktail of heatkilled bacteria, called “Coley’s Toxins”, to treat patients with osteosarcomaTalkin’ Toxins: From Coley’s to Modern Cancer Immunotherapy
科利的毒素 华文百科
2010年8月3日 科利的毒素（也被称为科利的毒素，[1] 科利的疫苗，[2] COLEY疫苗，科利的液体或者混合细菌疫苗）是一种含有从物种杀死的细菌过滤的毒素的混合物链球菌为链球菌和Serratia Marcescens， 而得名威廉科利， 一个外科肿瘤学家在特殊外科医院他在19世纪后期开发了混合物作为治疗癌症2021年6月8日 Connor Coley is looking to change that dynamic The Henri Slezynger (1957) Career Development Assistant Professor in the MIT Department of Chemical Engineering is developing computational tools that would be able to predict molecular behavior and learn from the successes and mistakes It’s an intuitive approach and one Using computational tools for molecule discovery MIT 2023年9月8日 Goldman, S, Bradshaw, J, Xin, J, Coley, CW “Prefixtree decoding for predicting mass spectra from molecules” arXiv:230306470 (2023) Jin, T, Coley, CW Publications – Coley Research Group
COMMENTARY Coley's toxins in perspective Nature
2023年5月19日 Coley's toxins in perspective Charlie O Starnes ,,~, Despite Initial hopes, the efficacy of tumour necrosis factor in treating cancer patients has been disappointing But a more Coley is a versatile white fish with a firm bite and mild flavour that’s great cooked on its own or used in fish pies, fish cakes and rice dishes like jambalaya Despite being championed by savvy chefs with an eye on sustainability, it remains a species with relatively low MSC sales in the UK and Ireland; only 307 tonnes in 202223, compared Eating coley in the UK Marine Stewardship Council MSC2023年11月30日 Coley Fillet 1kg £ 1495 Quick View Add to basket Quick View The flesh of coley is reasonably cheap, sometimes dull, offwhite, when raw, but lightens while cooking and with a nice flavour As coley has good firm flakes, it is great for pies and is ideal with a white sauce and covered with potato crust or pastryFrozen Coley, Buy Online, Fast Fish Seafood Delivery
Coley Bars and pubs in Bangsar, Kuala Lumpur Time Out
2016年6月15日 TueSat, 5pm12mn; Sun, 12nn7pm Coley has moved out from DRInc into its own swanky space just a few shoplots down the road Its new home is much more spacious and relaxing, complete with new2018年12月24日 Coley appeared a couple of years ago in the early days of the local speakeasy game It leveraged the hidden nature of those clandestine bars, tucked away in the back half of DrInc Café in Bangsar It was a small space that straddled cosy and crowded, outfitted with rattan chairs, Nala Designsesque motifs behind the bar and Review: Coley moves out, now a fullfledged bar in Bangsar2018年10月2日 由于Coley Toxin本就不是主流 (只对肉瘤等一部分类型的肿瘤有效)，也很少有医生愿意花费精力研究它的有效性 (60年代至今有过一些小规模相关临床 肿瘤免疫疗法是如何诞生的？36氪
肿瘤免疫治疗不稀奇，120年前就有了！Coley
2020年6月1日 Coley毒素最后没有获得推广的主要原因就是别人不能重复出他的成功。根据书里介绍，没有重复出来临床数据的原因有很多，比如毒素的制备没有标准化（浓度，有效成分），治疗的步骤也没有标准化（剂 2021年2月24日 图3所示。个病人Coley治疗故意诱导丹毒(Coley, 1896a)。颈部大病变经治疗后消失;患者保持健康8年，然后死于复发(Coley, 1909)。 虽然科利并不是个尝试用细菌感染治疗癌症的人(这一称号 感染细菌治好了绝症科利Connor W Coley Achieving autonomous multistep synthesis of novel molecular structures in chemical discovery processes is a goal shared by many researchers In this Comment, we discuss key Connor W Coley's research
What Ever Happened to Coley’s Toxins? Cancer Research
2015年4月2日 In 1965, the American Cancer Society added Coley’s toxins to its “Unproven Methods of Cancer Therapy” This inclusion effectively marked Coley’s toxins as beyond the pale among mainstream cancer researchers The ACS would eventually remove Coley’s Toxins from the list (10 years later) but by then the damage had been done以下是老外对英文名Coley的看法，并把英文翻译成中文，让大家知道 Coley 英文名外国人眼中是什么样的真实看法和感受！ Mango 译 每当在给孩子起英文名字的时候我都会犯难，幸好听取了起名专家的建议，这个Coley，我很喜欢，读音也很明亮，洋气感十足。Coley英文名Coley英文名什么意思科利Coley名字寓意起名网2022年9月30日 邵 峰 院 士 9月27日，美国癌症研究所公布2022年 威廉科利奖 （ William B Coley Award ）获奖者名单，我所邵峰院士因其在 细胞焦亡领域的原创性发现与其他三位杰出科学家Judy Lieberman，H ao Wu和Vishva Dixit共获殊荣。 他们的工作 发现了细胞焦亡过程中在膜上打孔的gasdermin蛋白家族（GSDM)，并发现细胞焦亡 邵峰院士荣获2022年威廉科利奖 新闻动态 北京生命科学
Revisiting Coley’s Toxins: Immunogenic Cardiolipins from
Coley’s toxins, an early and enigmatic form of cancer (immuno)therapy, were based on preparations of Streptococcus pyogenes As part of a program to explore bacterial metabolites with immunomodulatory potential, S pyogenes metabolites were assayed in a cellbased immune assay, and a single membrane lipid, 18:1/18:0/18:1/18:0 cardiolipin, 2023年11月27日 COLEY definition: any of various edible fishes , esp the coalfish Meaning, pronunciation, translations and examplesCOLEY definition and meaning Collins English Dictionary